Causes of Gynecomastia

So What are the Possible Causes of gynecomastia?

• Persistent pubertal gynecomastia – 25%
• Drugs – 10-25%
• No detectable abnormality – 25%
• Cirrhosis or malnutrition – 8%
• Primary hypogonadism – 8%
• Testicular tumors – 3%
• Secondary hypogonadism – 2%
• Hyperthyroidism - 1.5%
• Chronic renal insufficiency – 1%

Emmanuel De La Cruz M.D.

References:

Braunstein GD. Gynecomastia. N Engl J Med. Feb 18 1993;328(7):490-5

Mahoney CP. Adolescent gynecomastia. Differential diagnosis and management. Pediatr Clin North Am. Dec 1990;37(6):1389-404

Carlson HE. Approach to the patient with gynecomastia. J Clin Endocrinol Metab. Jan 2011;96(1):15-21